Journal: PLoS ONE

Article Title: Fibrin Clot Structure and Platelet Aggregation in Patients with Aspirin Treatment Failure

doi: 10.1371/journal.pone.0071150

Figure Lengend Snippet: CAD patients without previous MI compared with CAD patients with previous MI on aspirin (ATF) assesed by turbidimetric clot assays (n = 172) and Multiplate® aggregometry (n = 174), respectively. Results are presented as median±IQR.

Article Snippet: Platelet aggregation was evaluated by 1) multiple electrode aggregometry (MEA) using Multiplate® aggregometer (Dynabyte, Münich, Germany) with arachidonic acid (AA) 1.0 mM, collagen 1.0 μg/mL and adenosine diphosphate (ADP) 10 μM as agonists and by 2) the VerifyNow® Aspirin assay (Accumetrics, CA, USA) as previously described .

Techniques:

Journal: Journal of Atherosclerosis and Thrombosis

Article Title: Laboratory-Based Markers as Predictors of Brain Infarction During Carotid Stenting: a Prospective Study

doi: 10.5551/jat.31799

Figure Lengend Snippet: Studied laboratory markers

Article Snippet: PAI-1 polymorphism 4G/5G NA Rotor-gene 3000A (Corbett, Sydney, Australia) Multiplate aggregometry AA (U) 71.0–115.0 Hirudin blood tube 3.0 mL (Double wall) (Dynabyte GmbH, München, Germany) Multiplate 5.0 analyzator (Dynabyte GmbH, München, Germany) ADP (U) 57.0–113.0 Open in a separate window AA–arachidonic acid; ADP–adenosine diphosphate; EDTA–ethylenediaminetetraacetic acid; NA–not applicable; PAI-1–plasminogen activator inhibitor-1 caption a8 Studied laboratory markers The platelet function test was performed by the method of whole blood impedance aggregometry using a multiple platelet function analyzer, Multiplate.

Techniques: Activity Assay

Journal: Journal of Atherosclerosis and Thrombosis

Article Title: Laboratory-Based Markers as Predictors of Brain Infarction During Carotid Stenting: a Prospective Study

doi: 10.5551/jat.31799

Figure Lengend Snippet: Study results

Article Snippet: PAI-1 polymorphism 4G/5G NA Rotor-gene 3000A (Corbett, Sydney, Australia) Multiplate aggregometry AA (U) 71.0–115.0 Hirudin blood tube 3.0 mL (Double wall) (Dynabyte GmbH, München, Germany) Multiplate 5.0 analyzator (Dynabyte GmbH, München, Germany) ADP (U) 57.0–113.0 Open in a separate window AA–arachidonic acid; ADP–adenosine diphosphate; EDTA–ethylenediaminetetraacetic acid; NA–not applicable; PAI-1–plasminogen activator inhibitor-1 caption a8 Studied laboratory markers The platelet function test was performed by the method of whole blood impedance aggregometry using a multiple platelet function analyzer, Multiplate.

Techniques: Activity Assay

Journal: Frontiers in Pediatrics

Article Title: TEG Platelet Mapping and Impedance Aggregometry to Predict Platelet Transfusion During Cardiopulmonary Bypass in Pediatric Patients

doi: 10.3389/fped.2019.00509

Figure Lengend Snippet: Median values for TEG-PM Inhibition, TEG-PM MA, and MEIA at the ADP and AA receptors for each time point. The blue bars represent test results for patients who required platelet transfusion and the green bars represent patients who did not require platelet transfusion. Dashed reference lines on inhibition graphs signifying significant inhibition at 80%. Reference line on MEIA graph signifies 10% of the reference range for children 1–4 years of age . TEG-PM, thromboelastography with platelet mapping; MA, maximum amplitude; ADP, adenosine diphosphate receptor; AA, arachidonic acid receptor; MEIA, multiple electrode impedance aggregometry; AUC, area under the curve. °Outliers (1.5–3x IQR); *Extreme outliers (>3x IQR).

Article Snippet: Functional measures of hemostasis such as thromboelastography (TEG, Haemonetics Corp., Braintree, MA) and Multiple Electrode Impedance Aggregometry (MEIA, Verum Diagnostica, Roche, Munich, Germany) may be able to identify acquired platelet abnormalities and allow for goal-directed therapies that could reduce bleeding and the need for platelet and other blood product transfusions.

Techniques: Inhibition

Journal: Frontiers in Pediatrics

Article Title: TEG Platelet Mapping and Impedance Aggregometry to Predict Platelet Transfusion During Cardiopulmonary Bypass in Pediatric Patients

doi: 10.3389/fped.2019.00509

Figure Lengend Snippet: TEG-PM MA vs. MEIA AUC for the ADP Receptor at all sampling time points. TEG-PM MA, thromboelastography with platelet mapping maximum amplitude; ADP, adenosine diphosphate receptor; MEIA, multiple electrode impedance aggregometry; AUC, area under the curve.

Article Snippet: Functional measures of hemostasis such as thromboelastography (TEG, Haemonetics Corp., Braintree, MA) and Multiple Electrode Impedance Aggregometry (MEIA, Verum Diagnostica, Roche, Munich, Germany) may be able to identify acquired platelet abnormalities and allow for goal-directed therapies that could reduce bleeding and the need for platelet and other blood product transfusions.

Techniques: Sampling

Journal: Frontiers in Pediatrics

Article Title: TEG Platelet Mapping and Impedance Aggregometry to Predict Platelet Transfusion During Cardiopulmonary Bypass in Pediatric Patients

doi: 10.3389/fped.2019.00509

Figure Lengend Snippet: TEG-PM MA vs. MEIA AUC for the AA Receptor at all sampling time points. TEG-PM MA, thromboelastography with platelet mapping maximum amplitude; AA, arachidonic acid receptor; MEIA, multiple electrode impedance aggregometry; AUC, area under the curve.

Article Snippet: Functional measures of hemostasis such as thromboelastography (TEG, Haemonetics Corp., Braintree, MA) and Multiple Electrode Impedance Aggregometry (MEIA, Verum Diagnostica, Roche, Munich, Germany) may be able to identify acquired platelet abnormalities and allow for goal-directed therapies that could reduce bleeding and the need for platelet and other blood product transfusions.

Techniques: Sampling

Journal: Journal of Veterinary Internal Medicine

Article Title: Characteristics of hemostasis during experimental Ehrlichia canis infection

doi: 10.1111/jvim.15130

Figure Lengend Snippet: Dunnett's test results for the TF‐activated TEG, TF + tPA TEG, and whole blood impedance platelet aggregometry variables in beagles experimentally infected with E. canis

Article Snippet: For the multiple channel electrical impedance platelet aggregometry (Multiplate 5.0 Analyzer, Diapharma Group Inc), heparinized blood samples were kept at room temperature and analyzed within 40 minutes of blood collection (range, 29–40 minutes) for 12 minutes.

Techniques: Infection, Saline